Erythematous, scaly plaques, some with annular forms.

SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS

Subacute Cutaneous Lupus (SCLE) is a variant of lupus in which SSA (Ro) and SSB (La) antibodies are positive. It tends to occur in older woman, preferentially affects the trunk, and tends to have a papulosquamous morphology.

Drug-induced SCLE occurs.
Bacteria in the human microbiome may be triggers of lupus. Bacteria containing Ro orthologs have been found in lupus patients. CD4 memory cells from lupus patients are stimulated by Ro-containing bacteria.

Red, scaly, annular lesions, often on the upper trunk of a middle-aged woman, is typical. Lesions may appear as and be misdiagnosed as psoriasis.

Drug-Related

Various drugs have been reported to induce SCLE. The most compelling include terbinafine, hydrochlorothiazide and proton pump inhibitors, e.g. omeprazole.

SCLE sparing photoprotected skin.

Alopecia is a common clinical manifestation of SLE, with an incidence rate ranging from 17.3% to 85.2% depending upon the study. It can occur in various forms, including diffuse thinning as shown here in a patient with SCLE, patchy loss, and lupus hair (short, fragile hairs at the hairline).

RegionalDerm

It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.